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Tze-Chen Hsieh Selected Research

equiguard

1/2008Ethanolic extracts of herbal supplement Equiguard suppress growth and control gene expression in CWR22Rv1 cells representing the transition of prostate cancer from androgen dependence to hormone refractory status.
12/2004Equiguard suppresses androgen-dependent LNCaP prostate cancer cell proliferation by targeting cell cycle control via down regulation of the retinoblastoma protein Rb and induction of apoptosis via the release of cytochrome c.
5/2003Inhibition of proliferation and expression of AR/PSA by herbal supplement Equiguard in LNCaP cells cultured in androgen-proficient FBS and androgen-deficient charcoal-stripped FBS is correlated with increased serine-15 phosphorylation of the tumor suppressor gene p53.
4/2002Effects of herbal preparation Equiguard on hormone-responsive and hormone-refractory prostate carcinoma cells: mechanistic studies.

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Tze-Chen Hsieh Research Topics

Disease

22Neoplasms (Cancer)
01/2021 - 04/2002
14Prostatic Neoplasms (Prostate Cancer)
03/2020 - 03/2002
7Breast Neoplasms (Breast Cancer)
12/2011 - 11/2005
3Neoplasm Metastasis (Metastasis)
01/2021 - 11/2006
3Leukemia
01/2015 - 05/2008
2Colorectal Neoplasms (Colorectal Cancer)
10/2018 - 08/2017
2Inflammation (Inflammations)
01/2013 - 01/2011
2Atherosclerosis
11/2010 - 10/2005
2Carcinogenesis
07/2010 - 04/2002
2Carcinoma (Carcinomatosis)
08/2009 - 04/2002
1Circulating Neoplastic Cells
01/2021
1Neuroblastoma
01/2019
1Colonic Neoplasms (Colon Cancer)
10/2018
1Triple Negative Breast Neoplasms
10/2018
1Sarcoma (Soft Tissue Sarcoma)
08/2017
1Lung Neoplasms (Lung Cancer)
06/2016
1Medulloblastoma
02/2015
1Ovarian Neoplasms (Ovarian Cancer)
08/2013
1Multiple Myeloma
01/2013
1Congenital Abnormalities (Deformity)
01/2013
1Leprosy (Hansen's Disease)
01/2013
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2012
1Chronic Disease (Chronic Diseases)
12/2011
1Cardiovascular Diseases (Cardiovascular Disease)
01/2011
1Skin Neoplasms (Skin Cancer)
08/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2008
1Retinoblastoma (Glioblastoma, Retinal)
09/2008
1Stroke (Strokes)
05/2008

Drug/Important Bio-Agent (IBA)

16ResveratrolIBA
03/2020 - 10/2005
7PolyphenolsIBA
11/2019 - 08/2009
7AndrogensIBA
01/2012 - 04/2002
6Estrogen ReceptorsIBA
12/2011 - 11/2006
6Hormones (Hormone)IBA
11/2009 - 04/2002
5PhytochemicalsIBA
03/2020 - 10/2005
5Androgen Receptors (Androgen Receptor)IBA
10/2009 - 04/2002
4Proteins (Proteins, Gene)FDA Link
01/2021 - 09/2008
43,3',4,5'-tetrahydroxystilbeneIBA
11/2019 - 01/2012
4equiguardIBA
01/2008 - 04/2002
3Carrier Proteins (Binding Protein)IBA
01/2019 - 09/2008
3AntioxidantsIBA
10/2010 - 05/2008
3EnzymesIBA
10/2010 - 10/2009
3NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)IBA
07/2010 - 10/2008
3Prostate-Specific Antigen (Semenogelase)IBA
12/2004 - 04/2002
2salinomycinIBA
01/2019 - 01/2013
2NRH - quinone oxidoreductase2IBA
11/2018 - 07/2010
2DNA (Deoxyribonucleic Acid)IBA
10/2018 - 12/2007
2Messenger RNA (mRNA)IBA
08/2017 - 01/2015
2Biological ProductsIBA
02/2015 - 01/2013
2Pharmaceutical PreparationsIBA
01/2013 - 01/2013
2TocotrienolsIBA
10/2010 - 07/2010
2plastochromanol 8IBA
07/2010 - 10/2008
2Thioctic Acid (Lipoic Acid)IBA
10/2008 - 05/2008
2Transcription Factors (Transcription Factor)IBA
09/2008 - 12/2004
2Retinoblastoma ProteinIBA
09/2008 - 12/2004
2NF-kappa B (NF-kB)IBA
11/2005 - 12/2004
2herbal preparation PC-SPESIBA
07/2002 - 03/2002
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
03/2020
1Cadherins (E-Cadherin)IBA
03/2020
1AntibodiesIBA
11/2019
1FlavonoidsIBA
11/2019
1NucleolinIBA
01/2019
1GlutaminaseIBA
11/2018
1nicotinamide-beta-ribosideIBA
11/2018
1quinone (benzoquinone)IBA
11/2018
1Oxidoreductases (Dehydrogenase)IBA
11/2018
1p38 Mitogen-Activated Protein KinasesIBA
10/2018
1Monoclonal AntibodiesIBA
10/2018
1StilbenesIBA
10/2018
1Metformin (Glucophage)FDA LinkGeneric
06/2016
1PrebioticsIBA
01/2016
1MicroRNAs (MicroRNA)IBA
02/2015
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
02/2015
1sulforaphaneIBA
01/2015
1Phosphotransferases (Kinase)IBA
08/2013
1Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
08/2013
1CeramidesIBA
08/2013
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2013
1Thalidomide (Thalomid)FDA Link
01/2013
1Therapeutic UsesIBA
01/2013
1Biomarkers (Surrogate Marker)IBA
01/2012
1IntegrinsIBA
12/2011
1Chemokine CCL11IBA
01/2011
1CytokinesIBA
01/2011
1Interleukin-13IBA
01/2011
1ChemokinesIBA
01/2011
1Vitamin EFDA LinkGeneric
10/2010
1Cell Cycle ProteinsIBA
07/2010
1GenisteinIBA
10/2009
1QuercetinIBA
10/2009
1MicronutrientsIBA
10/2008
1epigallocatechin gallate (epigallocatechin-3-gallate)IBA
10/2008
1Antineoplastic Agents (Antineoplastics)IBA
09/2008
1delta tocotrienolIBA
09/2008
1Cyclin D1IBA
09/2008
1A-Form DNA (A-DNA)IBA
09/2008
1Sepharose (Agarose)IBA
01/2008
1Cell ExtractsIBA
01/2008

Therapy/Procedure

5Therapeutics
01/2021 - 12/2004
1Oral Administration
08/2017
1Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2011